ABSTRACT
Plants have always been used as a remedy for various illnesses and their widespread use is because they are safe, effective, and affordable when compared to allopathic medications. Nigella sativa is considered as a miracle herb and is accepted as a panacea in Middle East and South Asian countries. Numerous therapeutic benefits of the plant extract against diabetes, hypertension, pediatric seizures, opioid dependence, anxiety, arthritis, various infectious diseases, infertility, dyspepsia, asthma, allergic rhinitis were demonstrated by clinical studies. The bronchodilating property of few constituents of the seeds contributes its potency against different illnesses of the respiratory system, including asthma, dyspnea, nasal dryness, and rhinitis. According to the World Health Organization (WHO), respiratory diseases are second to cardiovascular disease and make up to five of the 30 most common causes of deaths worldwide. Currently, there is no cure to the chronic respiratory diseases, but various forms of treatments may help to ameliorate the quality of life of people suffering with the condition. An increasing number of people are approaching toward natural remedy to improve their respiratory symptoms, this review is planned to summarize all the therapeutic benefits of N. sativa against different respiratory illnesses which were characterized by experimental and clinical studies. © 2022 Elsevier Inc. All rights reserved.